Patients suffering with finger pain caused by Raynaud’s Syndrome are needed to participate in a clinical trial at Southern Illinois University School of Medicine’s Division of Plastic Surgery.

The randomized, double-blind clinical trial examines the effect of using Botox® to relieve pain by increasing blood flow. SIU is the only site in the United States participating in this study that evaluates the effectiveness and safety of Botox® on Raynaud’s patients with ischemic digits. 

Raynaud’s syndrome is a disorder that can affect the blood vessels in the fingers, toes, ears and nose. This disorder is characterized by episodic attacks that cause ischemia (constricted blood vessels).

According to principal investigator Dr. Michael W. Neumeister, professor and chair of SIU’s Division of Plastic Surgery, “In the hands, the limited blood flow can cause the fingers to turn cold, white and/or blue and be very painful, possibly even cause sores or ulcers to form. Our hope into the future is that we’ll find relief for these patients.”

To be eligible for the study, patients must be between the ages of 18 and 75 and be diagnosed with Raynaud’s Syndrome, including having results of an upper extremity angiogram. Participants must be willing to return to Springfield for treatment and evaluation for at least one month and follow up by phone for the remaining five years.

There are costs associated with participation. Participants or their insurance will be billed for standard treatment and clinic visits. Botox® will be provided at no cost to participants. There will be no charge for follow-up visits conducted by telephone. This study is funded by The Memorial Medical Center Foundation.

If you are interested in participating in the study, call Jenny at 217-545-7014 weekdays 7 a.m. – 3 p.m.


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